The college was financed with governmental and private support from local philanthropists. As one of the oldest medical colleges of Pakistan, it has produced several generations of doctors and dentists. The city of Multan is one of the hottest localities of Pakistan; this is reflected in architecture of the college and hospital high ceilings and large windows are commonplace. The college itself is spacious, with the various academic departments housed around a central quadrangle. The quadrangle is a large garden used for student functions and gatherings. There is an attached hospital, adjacent hostels, and faculty residential colony. The college as well as the hostels are nostalgic of old Islamic architecture. The buildings added to the campus in the 1960s to early 1980s were designed by A. R. Hye.